18 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically ... Diagnosis and Treatment ... #HES #Hematology ... #eosinophilia # ... eosinophils #diagnosis
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... Allergies): - Allergic ... Rhinitis - Allergic ... Hypereosinophilic Syndrome ... #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... (common causes ... are asthma, allergy ... glucocorticoid treatment ... Differential #diagnosis #hematology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... than 1500 and clinical ... Secondary Causes ... : - Allergic disorders ... #diagnosis #hematology
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Reaction with Eosinophilia ... associated with allergic ... medication (in this case ... #Dermatology #SkinRash ... #DRESS #Syndrome
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Reaction with Eosinophilia ... associated with allergic ... medication (in this case ... #Dermatology #SkinRash ... #DRESS #Syndrome
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
validated for VTE treatment ... studies suggest net clinical ... benefit of anticoagulation ... Bleeding #Risk #Scores ... #Factors #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... only curative treatment ... Myelodysplastic #Syndrome ... #hematology #oncology
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
ESRD & CAD • Eosinophilic ... cell activation syndrome ... Mastocytosis • Other hematologic ... Differential #Diagnosis #hematology ... #allergy
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Reaction with Eosinophilia ... associated with allergic ... medication (in this case ... #Dermatology #SkinRash ... #DRESS #Syndrome