81 results
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
Airway epithelial cells ... cytokines that promote dendritic ... These T cells then ... induce B-cell class ... #asthma #pathophysiology
How dendritic cells (DCs) orchestrate adaptive immunity
1- Sensing of microbial and damage signals by DCs
2- Phenotypic
How dendritic cells ... pathways 4- T cell ... immunity #immunology #pathophysiology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Differential Diagnosis Algorithm ... - Increased Cell ... imports K+ into cells ... Differential #Diagnosis #Algorithm ... potassium #low #pathophysiology
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
Pathogenesis and Clinical ... Ag-presenting cells ... (such as dendritic ... or plasma cells ... Humoral #Immunity #pathophysiology
Systemic Lupus Erythematosus (SLE): Pathogenesis

 • Genetic factors (Mutations in HLA- DR2/HLA-DR3 genes, complement genes, cytokine
dysfunction of dendritic ... cells, B-cells, ... T-cells) • Auto-antibodies ... Auto-reactive T-cells ... Erythematosus #SLE #Pathophysiology
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Pathogenesis and Clinical ... Natural Killer Cells ... • Humoral: (B cell ... : (T cell response ... #Inflammation #pathophysiology
Asthma: immunopathogenesis. 
Allergens attach to, and are taken up by, dendritic cells that he the respiratory
are taken up by, dendritic ... cells that he the ... T-helper (TH2) cells ... -4 activates B cells ... immunopathogenesis #Pathophysiology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... Reed-Sternberg (RS) Cells ... ~10% - B-Cell ... Classification #pathophysiology ... #differential #algorithm
Hypercalcemia of Malignancy - Pathophysiology
PTH-mediated
 • Parathyroid cancer
 • Ectopic production: Small cell lung cancer, ovarian
of Malignancy - Pathophysiology ... production: Small cell ... of lung, Renal Cell ... Hypercalcemia #Malignancy #Pathophysiology ... Differential #Diagnosis #algorithm
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Pathogenesis and clinical ... is entirely T-Cell ... allergen-specific T-Cell ... harmful -> Th Cells ... Allergy #Immunology #pathophysiology