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diagnosis symptoms differential management rheumatology blood bulimianervosa caudaequina classification hematuria henochscholeinpurpura hsp lupus manifestations mucocutaneous myelitis nephrology neurology pagetsdisease psychiatry
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
IgA Vasculitis – ... periumbilical region), nausea ... nephrotic/nephritic syndrome ... #Pathophysiology ... #Diagnosis #Signs
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
Glomerular Bleeding - IgA ... Mesangioproliferative GN without IgA ... pain hematuria syndrome ... hematuria • Signs ... Diagnostic of GN or vasculitis
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... disc herniation (central ... / Symptoms / Complications ... #MSK #pathophysiology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Schonlein Purpura (IgA ... tract, and often causes ... : • Behçet Syndrome ... • Cogan Syndrome ... purpura: strong sign
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... Schonlein Purpura (IgA ... tract, and often causes ... • Behcet syndrome ... • Cogan syndrome
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... Livedo Reticularis, Vasculitis ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... , and possibly renal ... symptoms are not caused ... anterior/posterior MSK ... Diagnosis #Management #Signs
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Xerostomia • Dental ... ) • Cutaneous vasculitis ... phenomenon (16%) MSK ... lubricants • Pharmacologic
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
10-33% develop MS ... monophasic Pathophysiology ... • Bilateral signs ... • Infectious causes ... - Sjogren - Vasculitis
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... bone formation MSK ... PagetsDisease #pathophysiology ... #diagnosis #signs ... #symptoms #complications
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