13 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... Chain deposition disease ... Lupus Erythematosus ... #differential # ... hematology
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
for Sweet Syndrome ... onset of tender erythematous ... underlying hematologic ... inflammatory disease ... #Hematology #Dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... GPA causes disease ... #Dermatologic ... Polyangiitis #GPA #dermatology ... #rheumatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Bone marrow disease ... : Schamberg Disease ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Diagnosis: • ANCA-associated ... diseases (i.e. ... Malignancy (e.g. hematologic ... vein thrombosis Hematologic ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
(Granulomatous disease ... Diagnosis: Systemic ... rheumatic diseases ... differential #diagnosis ... #rheumatology #
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... • Low serum C4 complement ... lupus erythematosus ... #types #classification ... #rheumatology #
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome ... disease. ... , breast CA - Hematologic ... #Syndrome #diagnosis ... #dermatology #oncology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... diseases, such ... #Differential #Diagnosis ... #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
multisystemic disease ... associated with other diseases ... demyelinating disease ... Nephrogenic DI Hematologic ... #Rheumatology #