22 results
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Diseases: • GATA2 ... Autoimmune Diseases ... : • Systemic lupus ... erythematosus ... #Diagnosis #Hematology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
polychondritis, Behcet's Disease ... ) • Rheumatic Diseases ... : IgG4-Related Disease ... lupus erythematosus ... #Diagnosis #rheumatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
- Systemic and ... Cholestatic liver disease ... Myelodisplastic syndrome ... Psychiatric Disease ... #generalized #dermatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Bone marrow disease ... : Schamberg Disease ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... Chain deposition disease ... Lupus Erythematosus ... #differential # ... hematology
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
for Sweet Syndrome ... onset of tender erythematous ... inflammatory disease ... treatment with systemic ... #Hematology #Dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
(Granulomatous disease ... Diagnosis: Systemic ... rheumatic diseases ... differential #diagnosis ... #rheumatology #
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
presentation of the disease ... GPA causes disease ... Diagnosis: Vasculitis ... Polyangiitis #GPA #dermatology ... #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Decade Skin Disease ... Diagnosis: • ANCA-associated ... tissue disease ... diseases (i.e. ... #Diagnosis #Rheumatology
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Chronic hemolytic anemia ... multifactorial mechanisms Hematologic ... neurofibromatosis, vasculitis ... #Diagnosis #Differential ... #Causes