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dermatology aortitis arteritis cryoglobulinemia cryoglobulins dermatologic erythematosus gca giantcell glomerulonephritis granulomatosis lupus nonpalpable palpable polyangiitis progressive purpura rapidly rash rpgn
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
(C-ANCA): GPA > ... Glomerulonephritis #Vasculitis ... #differential # ... diagnosis #algorithm ... #rheumatology
ANCA-Associated Vasculitis There are many definitions, but most come down to the presence of granulomas (pathologically or
Vasculitis There ... pathologically or clinically ... #Vasculitis #differential ... #diagnosis #algorithm ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis: + MPO-ANCA ... (Dx: GPA, EGPA, ... differential #diagnosis ... #rheumatology # ... classification
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Non-Infectious Aortitis: • Vasculitides ... Nodosa (PAN), ANCA ... associated vasculitis ... irAEs) (rare), Idiopathic ... #Diagnosis #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Leukocytoclastic vasculitis ... • Ig A vasculitis ... HCV, HBV Not Vasculitis ... #Diagnosis #hematology ... #rheumatology #
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
• Pauci-immune vasculitis ... Diagnosis: Vasculitis ... Granulomatous vasculitis ... • Necrotising vasculitis ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Diagnosis Framework ... Differential Diagnosis ... - interstitial keratitis ... Diagnosis #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• IgA vasculitis ... Hypersensitivity vasculitis ... • Vasculitis ... #rheumatology # ... vasculitis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Diagnosis: • ANCA-associated ... vasculitis, rheumatoid ... • Mesenteric vasculitis ... inflammation Cutaneous Vasculitis ... #Rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic inflammatory vasculitis ... Diagnosis = clinical ... diagnosis = vasculitis ... them, but urgent rheumatology ... #Management
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