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antibodies antibody antinuclear aortitis cryoglobulinemia cryoglobulins diseases glomerulonephritis rapidly rpgn sle systemic types vasculitides
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... ) • Systemic lupus ... erythematosus ... Jcortesizaguirr #ANA ... #rheumatology #
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
(C-ANCA): GPA > ... > eGPA • MPO-ANCA ... (P-ANCA): eGPA, ... diagnosis #algorithm ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
proteinuria, rapidly progressing ... often causes arthritis ... differential #diagnosis ... #rheumatology # ... classification
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Diagnosis Framework ... Nodosa (PAN), ANCA ... (RA), Systemic lupus ... erythematosus ( ... #Diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
findings (ANA, ... Skin Disease Classification ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... #Diagnosis #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
DDX: • ANCA (Antineutrophil ... (e.g. systemic lupus ... erythematosus ( ... #types #classification ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... ischemia • Skin: Erythematous ... often causes arthritis ... Diagnosis #Rheumatology
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