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algorithm champs complement diffuse extravascular hemolysis hemolytic hodgkins intravascular lymphadenopathy management mcv mds monoclonal myelodysplasia myelodysplastic paraproteinemias sle syndromes systemic
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Erythematosus ( ... #Low #Complement ... #diagnosis #differential ... #hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
• Systemic Lupus ... Erythematosus ... Lymphadenopathy #LAD ... #Causes #Hematology ... #Oncology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Low Mean Corpuscular ... Thalassemia • Lead ... #MCV #Classification ... #Causes #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low ... Skin Disease Classification ... permanent alopecia Differential ... PLT • Anemia of ... #Diagnosis #Rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... usually IgG) (e.g. lupus ... , CLL, lymphoma, ... #differential # ... diagnosis #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
) Classification ... may be high or low ... Immunohistochemical studies (to differentiate ... #diagnosis #classification ... #hematology #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
(-) hemolytic anemia ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... erythematosus, ... • Complement (Low ... #diagnosis #rheumatology ... #classification
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... compounds, alcohol, lead ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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