10 results
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
- Generalized Differential ... : • Lymphoma ... Myelodisplastic syndrome ... #secondary #systemic ... #generalized #dermatology
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
Eosinophilia - Differential ... Eosinophilia: • Primary ... familial eosinophilia Secondary ... ), Heme malig (AML ... ), Systemic mastocytosis
Causes of Eosinophilia - Differential Diagnosis
Bugs:
 - Fungus (aspergillosis)
 - Viral (HIV)
 - Ectoparasites (scabies, myiasis)
Rhinitis - Allergic Dermatitis ... : - CML - Lymphomas ... - Systemic Mastocytosis ... Hypereosinophilic Syndrome ... Diagnosis #Causes #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
+ distinctive primary ... • Tumor lysis syndrome ... bone marrow and secondary ... #Leukemia #Hematology ... #Oncology #Diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... febrile neutrophilic dermatosis ... initiation • Differential ... #management #hematology ... #oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Marginal Zone Lymphoma ... • Neutrophilic dermatosis ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Pruritus - No Primary ... : • Lymphoma ... Myelodisplastic syndrome ... #systemic #generalized ... #dermatology #Differential
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Vaginal dryness • Primary ... other diseases • Secondary ... ab (specific in primary ... Nephrogenic DI Hematologic ... Diagnosis #Management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... permanent alopecia Differential ... Angioimmunoblastic T-cell lymphoma ... the context of primary
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... reconstituted immune system ... : encephalitis secondary ... #Differential # ... Diagnosis #Management