11 results
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Chronic lung disease ... Gastrointestinal inflammatory disease ... Granulomatous disease ... • Liver diseases ... interstitial lung disease
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... weeks without infection ... cells can indicate disease ... lymphoproliferative disorders ... #workup #oncology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Rare Disorder: ... Causes: - Idiopathic ... (malignancy), lymphoma ... #oncology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... • Autoimmune disorders ... - Clinical Presentation ... number of sites of disease ... #hematology #oncology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Decade Skin Disease ... diseases (i.e. ... (e.g. thyroid disease ... ) • Kikuchi disease ... • Castleman's disease
Nail Pathologies - Findings in or Near Nails

Paronychia 

A superficial infection of the proximal and lateral
congenital heart disease ... interstitial lung disease ... inflammatory bowel diseases ... Seen in liver disease ... #Diagnosis #Clinical
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
with autoimmune diseases ... including coronavirus disease ... Systemic rheumatic diseases ... of associated disease ... #rheumatology #
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... Myeloproliferative Disease ... • Parvovirus infection ... #diagnosis #hematology ... #oncology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
neurological lesion: Clinical ... Infections: - ... Sarcoidosis, Behcet disease ... MCTD, Sjogren syndrome ... differential #algorithm
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
• Heavy chain disease ... changes (POEMS syndrome ... plasmacytoma • Castleman disease ... Sarcoidosis) • Liver disease ... #differential #diagnosis