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hematology management differential atlas chronic classification cll common cord cryofibrinogenemia cvid dermatology diseases erythematosus fingernails gap globulin hodgkins hypogammaglobulinemia immunodeficiency
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... to 8 years Clinical ... hepatitis • Lymphoma ... • Nodules • Lymphoid ... DDX - Other causes
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... weeks without infection ... cells can indicate disease ... lymphoproliferative disorders ... #workup #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... • Autoimmune disorders ... - Clinical Presentation ... number of sites of disease ... #hematology #oncology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Rare Disorder: ... Causes: - Idiopathic ... (malignancy), lymphoma ... #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... fibromyalgia) • Infections ... Clinical Features ... #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... Myeloproliferative Disease ... • Parvovirus infection ... #diagnosis #hematology ... #oncology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
neurological lesion: Clinical ... Infections: - ... Sarcoidosis, Behcet disease ... MCTD, Sjogren syndrome ... differential #algorithm
Nail Pathologies - Findings in or Near Nails Paronychia A superficial infection of the proximal and lateral
the Fingers Clinically ... seen in Reiter's syndrome ... or chemical dermatitis ... #Abnormal #Pathology ... #Diagnosis #Clinical
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulinemia Associated Disorders ... Malignancy • Infections ... : • + Clinical ... cryoglobulins • Negative causes ... Antiphospholipid syndrome
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Amyloidosis • Lymphoma ... changes (POEMS syndrome ... Include: • Viral infections ... Connective tissue disorders ... #differential #diagnosis
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