14 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... younger pts) Differential ... Diagnosis Monoclonal ... hemolytic #anemia #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
syndrome (Clinical ... disease) Differential ... #Syndrome #diagnosis ... #management #signs ... #symptoms #rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Lymphoma (HCV) • CLL ... • Heavy Chain disease ... • Neutrophilic dermatosis ... #Monoclonal #Differential ... #Diagnosis #Oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
immunophenotype Clinical ... chemotherapy for low-risk disease ... fludarabine) 3) Monoclonal ... Lymphocytic #Leukemia #oncology ... #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
febrile neutrophilic dermatosis ... : >3 symptoms, or ... initiation • Differential ... #management #hematology ... #oncology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
neurological lesion: Clinical ... Non-compressive Spinal Cord Causes ... - Sarcoidosis, Behcet ... disease - SLE ... MCTD, Sjogren syndrome
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Myeloproliferative Disease ... blood count with differential ... #diagnosis #hematology ... #oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Diagnosis Framework ... tract, and often causes ... VASCULITIS: • Behçet ... Presentation - Systemic Symptoms ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... • Progressive symptoms ... tract, and often causes ... vasculitis • Behcet ... #Diagnosis #Rheumatology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Shock, Autoimmune disease ... Neurological symptoms ... Reversible course Differential ... the underlying cause ... #diagnosis #management