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diagnosis differential rheumatology algorithm aplastic apml cancer chronic classification dermatology differentiation encephalopathy hodgkins immune inflammatory iris leukemia lymphocytic lymphoma mds
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... age 70 years Symptoms ... Myeloproliferative Disease ... #diagnosis #hematology ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... weeks without infection ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... marrow-failure syndromes ... myelodysplastic syndrome ... #oncology #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome ... (Sweets Syndrome ... Sweet syndrome ... classical Sweet syndrome ... #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Imaging: CXR- pulmonary ... Diagnosis: >3 symptoms ... Differentiation #Syndrome ... #hematology #oncology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Lady Windermere Syndrome ... : • Syndrome of ... Bone Marrow - Anemia ... Disease: Clinical
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Encephalopathy Syndrome ... Syndrome, characterized ... syndrome by 24 ... Paraneoplastic syndrome ... Encephalopathy #Syndrome
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Mucocutaneous lymph node syndrome ... tract, and often causes ... vasculitis • Behcet ... syndrome: Recurrent ... vasculitis • Cogan syndrome
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
common • Sjogren’s syndrome ... • MAGIC syndrome ... • Vexus syndrome ... Nodosa, GCA, Sweet syndrome ... disease • Infections
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... worsening of that disease ... initiation Clinical ... #Inflammatory #Syndrome ... Differential #Diagnosis #Management
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