10 results
Causes of Apparent Life Threatening Event (ALTE) - Differential Diagnosis Algorithm
Cardiac:
 • Congenital Heart Disease
 •
Congenital Heart Disease ... Arrhythmia • Cardiomyopathy ... age-dependent) Infectious ... Respiratory Tract Infection ... Tract Infection
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Myelogenous Leukemia • Primary ... Myelofibrosis Infectious ... • Rheumatic disorders ... • Celiac disease ... #Causes #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Bone marrow disease ... SLE) - Viral infections ... APLS • Acute Infectious ... : Schamberg Disease ... #Diagnosis #hematology
Right-Sided Heart Failure - Differential Diagnosis Algorithm
Cardiac Causes - Rule out Left-Sided Heart Failure (Most Common):
Obstructive Pulmonary Disease ... • Diffuse Lung Disease ... • Chronic Lung Infection ... Veno-Occlusive Disease ... #Cardiology #Differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
cold agglutin disease ... Mycoplasma pneumoniae infection ... e.g. sickle cell disease ... spherocytosis) • Infections ... diagnosis #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Chronic lung disease ... • Infectious ... Granulomatous disease ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
procedures - Infection ... PT, aPTT(liver disease ... bypass), LFT (liver disease ... hematologic disorder ... #Workup #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
but elevated as disease ... pregnancy, Cardiac diseases ... fungal, viral infections ... , IgG4 related disease ... #workup #hepatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
rheumatic diseases ... to exclude are infections ... Recurrent middle ear infections ... , recent viral infection ... #Diagnosis #Rheumatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... • Autoimmune disorders ... number of sites of disease ... classification #hematology ... #oncology #management