14 results
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Autoimmune Hemolytic anemia ... • Ex: Systemic Lupus ... #Allergic #Reactions ... #Types #Classification ... #Diagnosis #Definitions
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
Diagnosis Algorithm ... • Contact dermatitis ... Bullous systemic lupus ... Vesiculobullous #SkinRash ... #Diagnosis #Algorithm
Eczematous Skin Rash - Differential Diagnosis Algorithm
Eczematous - Pruritic/Scaly/Erythematous lesions. Usually poorly demarcated
 • Atopic Dermatitis
Eczematous Skin Rash - Differential ... Diagnosis Algorithm ... anyone - Allergic ... #Eczematous #SkinRash ... #Diagnosis #Algorithm
Pediatric Mouth Disorders - Differential Diagnosis Algorithm
Teeth:
 • Teething
Painful - Gastrointestinal:
 • Crohn's Disease
 • Ulcerative
- Differential ... Diagnosis Algorithm ... Inflammation: • Allergic ... Reaction #Mouth ... Diagnosis #Algorithm
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
, and drug allergies ... , and systemic lupus ... - Contact dermatitis ... Hypersensitivity #Types #Classification ... #Diagnosis #Reactions
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... Diagnosis Algorithm ... • RBC Membrane Disorder ... #Classification ... #Diagnosis #Algorithm
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... hemolysis, deficiency anemia ... post-splenectomy, Exercise, Allergic ... #Diagnosis #Algorithm
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... usually IgG) (e.g. lupus ... lymphoproliferative disorders ... Extravascular #Causes #differential ... #anemia
Skin Ulcers by Etiology - Differential Diagnosis Algorithm
Physical:
 • Trauma
 • Pressure
 • Radiation
Vascular:
 • Arterial
Diagnosis Algorithm ... • Factitious disorder ... • Sickle Cell Anemia ... Ulcers #ulcerative #skinrash ... #Diagnosis #Algorithm
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Testing Algorithm ... causes are asthma, allergy ... , drug reaction, ... #Algorithm #Differential ... #diagnosis #hematology