8 results
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
complexes • Ex: Systemic ... Lupus Erythematosus ... #Allergic #Reactions ... #Types #Classification ... #Diagnosis #Definitions
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
- Differential Diagnosis ... Algorithm Vesicles ... • Bullous systemic ... lupus erythematous ... Vesiculobullous #SkinRash
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
lgE antibodies ... lupus erythematosus ... - Contact dermatitis ... Hypersensitivity #Types #Classification ... #Diagnosis #Reactions
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Action: IgG/lgM antibodies ... glomerulonephritis, Systemic ... lupus erythematosus ... Examples: Contact dermatitis ... #table #classification
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Lupus Erythematosus ... Highly specific antibodies ... #Lupus #Erythematosus ... #diagnosis #rheumatology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
- Differential Diagnosis ... Algorithm Reactive ... • Systemic ... Lupus Erythematosus ... • Acne • Allergy
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... lupus erythematosus ... #Lupus #Erythematosus ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
lupus erythematosus ... disease, drug reactions ... C-ANCA) pattern: antibodies ... #rheumatology # ... classification