9 results
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
conjunctivitis Type ... complexes • Ex: Systemic ... Lupus Erythematosus ... Syndrome, Contact Dermatitis ... #Types #Classification
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
- Local and systemic ... lupus erythematosus ... - Contact dermatitis ... #Classification ... #Pathophysiology
Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
Type III Hypersensitivity ... : • Systemic Lupus ... antigens are the cause ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
Differential Diagnosis Algorithm ... • Bullous systemic ... lupus erythematous ... Vesiculobullous #SkinRash ... #causes
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
lgE causes mast-cell ... glomerulonephritis, Systemic ... lupus erythematosus ... Examples: Contact dermatitis ... #classification
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Reactive: - Systemic ... Lupus Erythematosus ... • Acne • Allergy ... #Causes #Hematology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... lupus erythematosus ... #classification ... #rheumatology #
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
febrile neutrophilic dermatosis ... Causes: - Idiopathic ... such as certain types ... CANDLE syndrome - Allergic ... ’s syndrome - Lupus
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... inflammation Others: • Lupus ... lupus erythematosus ... differential #diagnosis #rheumatology ... #classification