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differential types vasculitis allergy causes reactions activation cerebritis cns cryoglobulinemia cryoglobulins definitions dermatology diffuse lad lymphadenopathy macrophage mas neurology oncology
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
complexes • Ex: Systemic ... Lupus Erythematosus ... Syndrome, Contact Dermatitis ... Reactions #Types #Classification ... #Diagnosis #Definitions
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
lupus erythematosus ... - Contact dermatitis ... #Types #Classification ... #Pathophysiology ... #Allergy #Diagnosis
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions - Inflammatory
Algorithm Vesicles ... • Bullous systemic ... lupus erythematous ... Vesiculobullous #SkinRash ... #Diagnosis #Algorithm
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Algorithm Reactive ... • Systemic ... Lupus Erythematosus ... • Acne • Allergy ... #Hematology #Oncology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Lupus Erythematosus ... Disease, PRES Pathophysiology ... #Lupus #Erythematosus ... CNS #neurology #rheumatology ... #management #treatment
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Classification of ... vasculitis - hypersensitivity ... lupus erythematosus ... #Rheumatology # ... Diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... lupus erythematosus ... • Drug-induced hypersensitivity ... #Management #Hematology ... #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... vasculitis • Hypersensitivity ... lupus erythematosus ... #types #classification ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... ischemia - Skin: erythematous ... lupus erythematosus ... #rheumatology # ... classification
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
disorders, including systemic ... lupus erythematosus ... cell lymphoma Pathophysiology ... in LNs and the systemic ... #management #rheumatology
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