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management vasculitis classification hematology neurology algorithm behcet cerebritis cns cryoglobulins dermatology disorders erythematosus monoclonal nonpalpable oncology palpable paraproteinemias purpura signs
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Hyperviscosity Syndrome ... Syndrome: • Clinical ... syndrome in 80% ... Syndrome • Idiopathic ... 20% Sjögren's syndrome
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Kasabach-Merritt syndrome ... Pigmented Purpuric Dermatosis ... Gardner-Diamond syndrome ... /HSP • Cryoglobulinemia ... #Diagnosis #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
) Clinical Manifestations ... Demyelinating Syndrome ... Cerebrovascular Disease ... autoantibodies that will cause ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Mucocutaneous lymph node syndrome ... : • Behçet Syndrome ... • Cogan Syndrome ... differential #diagnosis ... #rheumatology #
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
capillary leak syndrome ... Hyperviscosity syndrome ... CVST • Bing-Neel syndrome ... (Dermato-neuro syndrome ... ) • Gleich syndrome
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome ... occlusion, Budd-Chiari syndrome ... tests in Behcet syndrome ... ) Differential Diagnosis ... adenopathy (PFAPA) syndrome
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
neurological lesion: Clinical ... Causes: 1. ... - SLE, Scleroderma ... MCTD, Sjogren syndrome ... #neurology #differential
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Differential Diagnosis ... Mucocutaneous lymph node syndrome ... • Behcet syndrome ... • Cogan syndrome ... #Differential #Diagnosis
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... overlaps with RA, SLE ... • Mikulicz syndrome ... enlargement Sjogren's Syndrome ... #Sjogrens #Syndrome
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