23 results
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... Cause Organ Damage ... : • Clinical triad ... (e.g. systemic lupus
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
Infectious manifestations ... Neutrophilic dermatosis ... (dermatomyositis ... #differential # ... #oncology #clinical
MIAMI Mnemonic for Differential Diagnosis of Lymphadenopathy
Malignancies
 - Kaposi sarcoma, leukemias, lymphomas, metastases, skin neoplasms
Infections
 -
lymphomas, metastases, skin ... toxoplasmosis Autoimmune ... disorders - Dermatomyositis ... arthritis, Sjögren syndrome ... disease, systemic lupus
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
febrile neutrophilic dermatosis ... Episcleritis Signs ... Causes: - Idiopathic ... multiforme - Dermatomyositis ... - Lupus - Leukemia
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANAAutoimmune ... likely it will be clinically ... , Polymyositis/Dermatomyositis ... #rheumatology #diagnosis ... #differential
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Allopecia - Differential ... Diagnosis Framework ... , Loose anagen syndrome ... Examination: • Signs ... DHEAS) • ANA
Waterborne Infections - Differential Diagnosis Framework

Infections that can be acquired from fresh water, brackish water, sea
- Differential ... Diagnosis Framework ... Hemolytic Uremic Syndrome ... Blooms (HABs) Skin ... is biphasic • Clinical
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Palpable Rash: - Autoimmune ... Vasculitis (lupus ... immunoglobulins & cryoglobulins ... • Skin biopsy
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Diagnosis Framework ... Lack of UMN/LMN signs ... necrotizing myopathy • Autoimmune ... cryoglobulins ... Muscle Biopsy: Dermatomyositis
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
associated with autoimmune ... Malignancy • Infections ... : • + Clinical ... • Negative causes ... Antiphospholipid syndrome