14 results
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... Cause Organ Damage ... : • Clinical triad ... (e.g. systemic lupus
MIAMI Mnemonic for Differential Diagnosis of Lymphadenopathy
Malignancies
 - Kaposi sarcoma, leukemias, lymphomas, metastases, skin neoplasms
Infections
 -
lymphomas, metastases, skin ... toxoplasmosis Autoimmune ... disorders - Dermatomyositis ... arthritis, Sjögren syndrome ... disease, systemic lupus
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
febrile neutrophilic dermatosis ... Episcleritis Signs ... Causes: - Idiopathic ... multiforme - Dermatomyositis ... - Lupus - Leukemia
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
of the spinal cord ... Lack of UMN/LMN signs ... necrotizing myopathy • Autoimmune ... cryoglobulins ... Muscle Biopsy: Dermatomyositis
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
associated with autoimmune ... Malignancy • Infections ... : • + Clinical ... • Negative causes ... Antiphospholipid syndrome
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Allopecia - Differential ... Diagnosis Framework ... Capitis - Skin ... , Loose anagen syndrome ... Examination: • Signs
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
causes arthritis ... to exclude are infections ... purpura: strong sign ... LFT • ESR • ANA ... Serologies for Cryoglobulins
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
neurological lesion: Clinical ... signs below the ... Causes: 1. ... Infections: - ... MCTD, Sjogren syndrome
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... Still disease, dermatomyositis ... fibromyalgia) • Infections
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
autoimmune disorder ... life-threatening Differential ... - Peek sign ... precipitated by: Drugs, infection ... #management #neurology