12 results
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... Syndrome: • Clinical ... (e.g. systemic lupus ... classification #rheumatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... Pigmented Purpuric Dermatosis ... vasculitis/HSP • Cryoglobulinemia ... #Diagnosis #hematology
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Allopecia - Differential ... Diagnosis Framework ... , Loose anagen syndrome ... Examination: • Signs ... DHEAS) • ANA
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Associated Disorders ... Malignancy • Infections ... • Negative causes ... Antiphospholipid syndrome ... #rheumatology #
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Rare Disorder: ... Episcleritis Signs ... Causes: - Idiopathic ... multiforme - Dermatomyositis ... - Lupus - Leukemia
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
causes arthritis ... to exclude are infections ... purpura: strong sign ... LFT • ESR • ANA ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... Still disease, dermatomyositis ... fibromyalgia) • Infections
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... , neurologic, and ... causes arthritis ... + MPO) Cryoglobulinemic ... #Diagnosis #Rheumatology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
autoimmune disorder ... life-threatening Differential ... - Peek sign ... precipitated by: Drugs, infection ... #management #neurology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
neurological lesion: Clinical ... signs below the ... Infections: - ... MCTD, Sjogren syndrome ... #diagnosis #neurology