7 results
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... Vascular Sludging ... : • Clinical triad ... lupus erythematosus
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
Vesiculobullous Skin ... foliaceus - Infectious ... • Bullous systemic ... lupus erythematous ... #causes
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... and bullous or vesicular ... lupus erythematosus ... to exclude are infections ... , and SLE) • Urinalysis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Still disease, dermatomyositis ... fibromyalgia) • Infections ... lupus erythematosus ... #Systemic #Lupus
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... diseases, such as SLE ... : Erythematous nodules ... and bullous or vesicular ... tract, and often causes
Causes of Purpura or Easy Bruising in Children

Platelet count reduced, i.e. thrombocytopenia
 - Increased platelet destruction
(systemic lupus ... erythematosus) ... and other severe infections ... - Vasculitis ... pediatrics #diagnosis #differential
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
neurological lesion: Clinical ... Infections: - ... Behcet disease - SLE ... , Scleroderma, Systemic ... #algorithm