10 results
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Syndrome (SS), Polymyositis ... #ANA #patterns ... #rheumatology #diagnosis ... #differential
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... : The ANA patterns ... #ANA #patterns ... #rheumatology #diagnosis ... #differential
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
SLE) Clinical ... Demyelinating Syndrome ... of Lupus Cerebritis ... #rheumatology # ... cerebritis #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... arthritis, weight loss ... alopecia Differential ... Diagnosis: • ANCA-associated ... #Diagnosis #Rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Workup: - ANA ... Erythematosus ( ... Workup: - ANA ... #table #rheumatology ... #diagnosis #management
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... searched for when ANA ... #erythematosus ... #diagnosis #rheumatology ... #table #ANA
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often causes arthritis ... Anorexia • Weight loss ... ) pattern: antibodies ... SLE) • Urinalysis ... #diagnosis #rheumatology
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Diagnosis Framework ... pattern hair loss ... , Loose anagen syndrome ... DHEAS) • ANA ... #Diagnosis #dermatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
diseases, such as SLE ... malaise, weight loss ... ischemia • Skin: Erythematous ... often causes arthritis ... #Diagnosis #Rheumatology
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
such as: • SLE ... Anti-Matrilin-1 Ab ○ Antibodies ... Nonspecific ↑ ESR, CRP, ANA ... Polychondritis #rheumatology ... #diagnosis #management