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neurology systemic treatment vasculitis algorithm antinuclear cerebritis cns cord disease disorders druginduced muscle myopathy patterns polychondritis relapsing sams signs spinal
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... likely it will be clinically ... Syndrome (SS), Polymyositis ... #rheumatology #diagnosis ... #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... alopecia Differential ... Diagnosis: • ANCA-associated ... #Diagnosis #Rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
SLE) Clinical ... Demyelinating Syndrome ... Secondary prevention (statin ... #rheumatology # ... #management #treatment
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
GBS), systemic lupus ... erythematosus ( ... SLE), polymyositis ... myopathy (IMNM) → Antibodies ... #management #treatment
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Erythematosus ( ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
VASCULITIS: • Behçet ... LFT • ESR • ANA ... SLE) • Urinalysis ... #diagnosis #rheumatology ... #classification
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
syndrome (Clinical ... disease) Differential ... #Syndrome #diagnosis ... #management #signs ... #symptoms #rheumatology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
neurological lesion: Clinical ... hypercoagulable states ... - Sarcoidosis, Behcet ... disease - SLE ... MCTD, Sjogren syndrome
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... ischemia • Skin: Erythematous ... • Progressive symptoms ... vasculitis • Behcet ... #Diagnosis #Rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
cases such as: • SLE ... Sarcoidosis • Behcet ... Nonspecific ↑ ESR, CRP, ANA ... Polychondritis #rheumatology ... #diagnosis #management
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