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diagnosis erythematosus management systemic antinuclear classification differential vasculitis activation antibodies autoantibodies cerebritis cns cryoglobulinemia cryoglobulins hematology macrophage mas neurology patterns
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Systemic lupus ... is clinically suspected ... overlap syndromes ... erythematosus #diagnosis #rheumatology ... #table #ANA
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... erythematosus (SLE ... ), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... #patterns #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... ) Clinical Manifestations ... Demyelinating Syndrome ... Erythematosus #SLE ... CNS #neurology #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Non-autoimmune rheumatologic ... Clinical Features ... Erythematosus #Diagnosis #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... diseases: - 10% SLE ... (e.g. systemic lupus ... erythematosus (SLE ... classification #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... Clinical Presentation ... SJIA], systemic lupus ... erythematosus [SLE ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... lesions-interstitial keratitis ... such as systemic lupus ... SLE) • Urinalysis ... differential #diagnosis #rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
the most common clinical ... cases such as: • SLE ... Diagnosis: • Clinical ... Nonspecific ↑ ESR, CRP, ANA ... Polychondritis #rheumatology
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