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diagnosis differential rheumatology dermatology causes classification cryoglobulinemia oncology cryofibrinogenemia cryoglobulinemic monoclonal paraproteinemias petechiae petechial physicalexam rash sweet vasculitides vesiculobullous
Diagnosis of Cryoglobulinemia Vasculitis 1) Presence of cryoglobulin Circulating immunoglobulins that precipitate with cold temperature and dissolve
1) Presence of cryoglobulin ... Cryoglobulins are ... with cryoglobulin ... Hyperviscosity syndrome ... #Diagnosis #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Vascular Sludging ... Hyperviscosity Syndrome ... Types: • Type ... (e.g. systemic lupus ... classification #rheumatology
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions - Inflammatory
Differential Diagnosis Algorithm ... • Contact dermatitis ... Bullous systemic lupus ... drug eruption #Vesicular ... Vesiculobullous #SkinRash
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... and bullous or vesicular ... lesions-interstitial keratitis ... such as systemic lupus ... Serologies for Cryoglobulins
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Differential Diagnosis Algorithm ... Disruptions in vascular ... Infection - Vasculitis ... (lupus, RA, Sjogren's ... immunoglobulins & cryoglobulins
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Hyperviscosity, - Vascular ... Divided Into Two Types ... malignancies, vasculitis ... Antiphospholipid syndrome ... #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Neutrophilic dermatosis ... to cold IgG • Lupus ... Subcorneal pustular dermatosis ... (Thrombosis in vascular ... Paraproteinemias #Hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
febrile neutrophilic dermatosis ... , breast CA - Hematologic ... such as certain types ... Leukocytoclastic vasculitis ... - Lupus - Leukemia
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