10 results
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
- Diagnosis Manifestations ... mimickers, Other auto-immune ... , Infectious diseases ... sclerosis, Still's disease ... autoantibodies #signs #symptoms
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... febrile neutrophilic dermatosis ... : >3 symptoms, or ... Differentiation #Syndrome #APML ... #diagnosis #management
A quick infographic on various pearls about atopic dermatitis, a disease with an increasing burden on
risk factors, management ... #treatment #diagnosis ... #dermatology #skinrash ... /hyperactivity symptoms ... J Allergy Clin Immunol
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... Evolution: Chronic disease ... #sle #comparison ... #rheumatology #diagnosis ... #management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Necrotizing, pauci-immune ... respiratory tracts Immune ... inflammation Others: • Lupus ... such as systemic lupus ... Presentation - Systemic Symptoms
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management ... survival is 93-95% Pathophysiology ... activity → local immune ... skin (16-32%): lupus ... #Management #Signs
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
worsening of that disease ... pericarditis, peritoneal disease ... leukoencephalopathy (PML ... ocular lesions: keratitis ... #Management
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... cells are the immune ... Presentation: - Disease ... fasciculations Common Symptoms ... #management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... activation of an immune ... • Immune Mediated ... Bilateral signs and/or symptoms ... #management #neurology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
including systemic lupus ... cell lymphoma Pathophysiology ... and the systemic symptoms ... Histopathological Diagnoses ... #management #rheumatology