11 results
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Gravis, Graves' Disease ... complexes • Ex: Systemic ... Lupus Erythematosus ... Syndrome, Contact Dermatitis ... Classification #Diagnosis
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
- Differential Diagnosis ... Algorithm Vesicles ... • Bullous systemic ... lupus erythematous ... Vesiculobullous #SkinRash
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
- Differential Diagnosis ... Algorithm Monoarthritis ... Lupus - with Systemic ... Lupus Erythematosus ... should have other symptoms
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
during hemolytic disease ... lupus erythematosus ... - Contact dermatitis ... Classification #Pathophysiology ... #Allergy #Diagnosis
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... lupus erythematosus ... Sjogrens #Syndrome #Pathophysiology ... #Diagnosis #Signs ... #Symptoms
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
reaction, Haemolytic disease ... glomerulonephritis, Systemic ... lupus erythematosus ... Examples: Contact dermatitis ... classification #comparison
A quick infographic on various pearls about atopic dermatitis, a disease with an increasing burden on
medications #treatment #diagnosis ... #dermatology #skinrash ... /hyperactivity symptoms ... Allergy. 2018;73 ... J Allergy Clin Immunol
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
months to years) Systemic ... Lupus Erythematosus ... Evolution: Chronic disease ... #sle #comparison ... #rheumatology #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
inflammation Others: • Lupus ... ischemia - Skin: erythematous ... as systemic lupus ... erythematosus, ... Symptoms (Sx) in
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
febrile neutrophilic dermatosis ... disease. ... CANDLE syndrome - Allergic ... contact dermatitis ... ’s syndrome - Lupus