13 results
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Immunological Target: Allergen ... Gravis, Graves' Disease ... • Ex: Systemic Lupus ... Syndrome, Contact Dermatitis ... Classification #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... inflammation Others: • Lupus ... lesions-interstitial keratitis ... Differential Diagnosis ... such as systemic lupus
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
during hemolytic disease ... , and systemic lupus ... - Contact dermatitis ... Classification #Pathophysiology ... #Allergy #Diagnosis
Interstitial Lung Diseases (ILD)
Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): 
 • Hypersensitivity pneumonitis, Farmer's lung, Bird
Interstitial Lung Diseases ... a.k.a. extrinsic allergic ... Polymyositis-dermatomyositis, Lupus ... Sarcoidosis • Vasculitis ... #ILD #diagnosis
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
reaction, Haemolytic disease ... glomerulonephritis, Systemic lupus ... Examples: Contact dermatitis ... reactions #types #allergy ... classification #comparison
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... Post-strep GN, Lupus ... involvement: Anti-GBM Disease ... Glomerulonephritis #Vasculitis ... #differential #diagnosis
A quick infographic on various pearls about atopic dermatitis, a disease with an increasing burden on
, a disease with ... medications #treatment #diagnosis ... #dermatology #skinrash ... Allergy. 2018;73 ... J Allergy Clin Immunol
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... Lung Abscess Pathophysiology ... in case of PCN allergy ... Blastomyces - Dermatitidis ... : • Vasculitis
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
febrile neutrophilic dermatosis ... with systemic disease ... CANDLE syndrome - Allergic ... Leukocytoclastic vasculitis ... ’s syndrome - Lupus
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... • Neutrophilic dermatosis ... to cold IgG • Lupus ... Sneddon-Wilkinson disease ... #Differential #Diagnosis