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differential rheumatology hematology vasculitis algorithm classification oncology champs complement cord cryofibrinogenemia cryoglobulins disorders hypocomplementemia low mnemonic monoclonal neurology nonpalpable palpable
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions - Inflammatory
• Bullous systemic ... lupus erythematous ... drug eruption #Vesicular ... Vesiculobullous #SkinRash ... #dermatology #Differential
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... • They can cause ... Cryoglobulins Cause ... Vascular Sludging ... lupus erythematosus
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Mnemonic C - Cryoglobulinemia ... glomerulonephritis (>90%) S - Systemic ... Lupus Erythematosus ... CHAMPS #Mnemonic #diagnosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Splenomegaly - CTD (SLE ... Pigmented Purpuric Dermatosis ... vasculitis/HSP • Cryoglobulinemia ... Associated - SLE
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Neutrophilic dermatosis ... to cold IgG • Lupus ... Subcorneal pustular dermatosis ... (Thrombosis in vascular ... #Differential #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... ANCA +MPO) • Cryoglobulinemic ... and bullous or vesicular ... lupus erythematosus ... vasculitis, and SLE
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
febrile neutrophilic dermatosis ... Causes: - Idiopathic ... such as certain types ... ’s syndrome - Lupus ... #dermatology #oncology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Divided Into Two Types ... processes: • Systemic ... Cryofibrinogenemia Diagnosis ... cryoglobulins • Negative causes ... Cryofibrinogenemia #diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... diseases, such as SLE ... and bullous or vesicular ... tract, and often causes ... / ANCA + MPO) Cryoglobulinemic
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
- Differential Diagnosis ... Non-compressive Spinal Cord Causes ... Actinomyces, Blastomyces dermatitidis ... Behcet disease - SLE ... , Scleroderma, Systemic
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