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Renal Involvement in Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Erythematosus ... Lupusreference #Renal #diseases ... #venn #nephrology ... #nephritis #classification ... #types #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
nephritis can present ... abnormalities (non-nephrotic ... hematuria) • Frank nephritis ... (nephrotic-range ... suspicion for nephritis
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Lupus Erythematosus ... nephritis, Class ... nephritis Immunologic ... #diagnosis #rheumatology
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
EM) Haematuria/nephritis ... • Lupus ISN/RPS ... Haemolytic-uraemic syndrome Nephrotic ... #nephrology #pathology ... #comparison #table
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
- systemic lupus ... erythematosus ... purpura-arthralgia-nephritis ... dermatomyositis #Size ... #Rheumatology #
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Association with disease ... nephritis. ... #erythematosus ... #diagnosis #rheumatology ... #table #ANA
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Erythematosus ( ... nephritis, NPSLE ... #sle #comparison ... #table #rheumatology ... #diagnosis #management