10 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
SLE) Clinical ... Demyelinating Syndrome ... Cerebrovascular Disease ... : • Inflammatory ... #SLE #CNS #neurology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
nervous system (CNS ... Inflammatory causes ... • Systemic lupus ... erythematosus ... #neurology #inflammatory
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
nervous system (CNS ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... Thromboembolism (7%) • CNS ... • Severe Liver Disease ... #treatment #management ... #hematology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Hypocomplementemia • Can cause ... ducts Clinical ... Adenocarcinoma Treatment ... Diagnosis #Management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Overview Focal inflammatory ... that results in CNS ... Transverse Myelitis - Clinical ... Transverse Myelitis Treatment ... Myelitis #diagnosis #management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
, such as SLE, atherosclerotic ... ischemia • Skin: Erythematous ... tract, and often causes ... chorioretinitis, CNS ... : Ocular inflammatory
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
including systemic lupus ... erythematosus ( ... SLE), Sjögren’s ... Hypoalbuminemia Treatment ... TAFRO #diagnosis #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Syndrome - Overview ... worsening of that disease ... initiation Clinical ... pleural effusions, CNS ... #Diagnosis #Management
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
the most common clinical ... Inflammatory ... as: • SLE • RA ... affected tissue Treatment ... #diagnosis #management