15 results
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... Gravis, Graves' Disease ... • Ex: Systemic Lupus ... , Contact Dermatitis
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
histiocytosis • Allergic ... AI: EGPA, IgG-4 disease ... , Behcet disease ... Chronic inflammatory disease ... Diagnosis #Algorithm #allergy
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... during hemolytic disease ... , and systemic lupus ... Pathophysiology #Allergy
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
Connective tissue disease-associated ... interstitial lung diseases ... PSS: Sjogren syndrome ... : systemic lupus ... connective tissue disease
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... reaction, Haemolytic disease ... Examples: Contact dermatitis ... reactions #types #allergy ... classification #comparison
Interstitial Lung Diseases (ILD)
Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): 
 • Hypersensitivity pneumonitis, Farmer's lung, Bird
Interstitial Lung Diseases ... a.k.a. extrinsic allergic ... Connective Tissue Disease ... connective tissue disease ... Interstitial #Lung #Diseases
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
Eosinophilic Lung Diseases ... loss, malaise • Allergic ... Hypereosinophilic Syndrome ... Eosinophilic #Lung #Diseases ... differential #diagnosis #comparison
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Demyelinating Syndrome ... Cerebrovascular Disease ... Erythematosus #SLE ... #CNS #neurology
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
selected glomerular diseases ... /nephritis • Lupus ... Minimal change disease ... RPGN • Anti-GBM disease ... #glomerular #diseases
A quick infographic on various pearls about atopic dermatitis, a disease with an increasing burden on
, a disease with ... inflammatory skin disease ... This disease imposes ... Allergy. 2018;73 ... J Allergy Clin Immunol