16 results
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Immunological Target: Allergen ... Gravis, Graves' Disease ... • Ex: Systemic Lupus ... Syndrome, Contact Dermatitis ... Classification #Diagnosis
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
ANA ≠ Autoimmune Disease ... • Rheumatic Diseases ... : Lupus (SLE), Systemic ... , Interstitial Pulmonary ... #rheumatology #diagnosis
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
Connective tissue disease-associated ... interstitial lung diseases ... rheumatoid arthritis SLE ... : systemic lupus ... connective tissue disease
Interstitial Lung Diseases (ILD)
Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): 
 • Hypersensitivity pneumonitis, Farmer's lung, Bird
Interstitial Lung Diseases ... Connective Tissue Disease ... connective tissue disease ... bronchiolitis-interstitial lung disease ... Interstitial #Lung #Diseases
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Peripheral edema, Disease-specific ... vasculitis, Behcet disease ... Goodpasture's Disease ... dysmorphic RBCs) • Disease-specific ... #nephrology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Cerebrovascular Disease ... permeability Diagnosis ... Erythematosus #SLE ... #CNS #neurology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
When the specific allergen ... during hemolytic disease ... , and systemic lupus ... - Contact dermatitis ... #Diagnosis #Reactions
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE)
SLE patient develops
- Diagnostic approach ... to kidney disease ... Non-LN Kidney Disease ... #Nephritis #diagnosis ... #nephrology #biopsy
A quick infographic on various pearls about atopic dermatitis, a disease with an increasing burden on
, a disease with ... inflammatory skin disease ... This disease imposes ... medications #treatment #diagnosis ... #dermatology #skinrash
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
disease, and ocular ... pain • Kawasaki Disease ... (Granulomatous disease ... atherosclerotic disease ... most important diseases