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differential causes management neurology rheumatology classification treatment cardiology infectiousdiseases syndrome algorithm cns dermatology endocarditis hemoptysis hypersensitivity ild lung reactions table
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... Gravis, Graves' Disease ... • Ex: Systemic Lupus ... Syndrome, Contact Dermatitis ... Classification #Diagnosis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
ANA ≠ Autoimmune Disease ... • Rheumatic Diseases ... : Lupus (SLE), Systemic ... , Interstitial Pulmonary ... #rheumatology #diagnosis
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
Connective tissue disease-associated ... interstitial lung diseases ... rheumatoid arthritis SLE ... : systemic lupus ... connective tissue disease
Interstitial Lung Diseases (ILD) Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): • Hypersensitivity pneumonitis, Farmer's lung, Bird
Interstitial Lung Diseases ... Connective Tissue Disease ... connective tissue disease ... bronchiolitis-interstitial lung disease ... Interstitial #Lung #Diseases
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
• Periodontal disease ... dentition/gingival disease ... loss • Late disease ... Gingival crevice disease ... in early disease
Hemoptysis - Differential Diagnosis Framework Airways: • Bronchitis • Bronchiectasis • Malignancy: Primary bronchogenic CA, Endobronchial
- Differential Diagnosis ... westermani, PNA, Lung abscess ... Goodpastures, Lupus ... syndrome • Valvular Disease ... #pulmonary #causes
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Peripheral edema, Disease-specific ... vasculitis, Behcet disease ... Goodpasture's Disease ... dysmorphic RBCs) • Disease-specific ... #nephrology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Cerebrovascular Disease ... permeability Diagnosis ... Erythematosus #SLE ... #CNS #neurology
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
lymphoproliferative disease ... nodules, may also see ... Syphilis • Pyogenic Abscess ... • Metastatic disease ... demyelinating diseases
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
When the specific allergen ... during hemolytic disease ... , and systemic lupus ... - Contact dermatitis ... #Diagnosis #Reactions
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