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diagnosis hematology classification causes hypersensitivity types algorithm dermatology table vasculitis allergic anemia appearance basophilia basophils color comparison definitions dialysis extravascular
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Gravis, Graves' Disease ... • Ex: Systemic Lupus ... Syndrome, Contact Dermatitis ... (ie. reaction to ... #Allergic #Reactions
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions - Inflammatory
Vesiculobullous Skin Rash - Differential ... Bullous impetigo - Reaction ... • Contact dermatitis ... Bullous systemic lupus ... Vesiculobullous #SkinRash
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Vasculitides, IBD, Celiac disease ... syndrome, POEMS • Reaction ... post-splenectomy, Exercise, Allergic ... reactions Matthew
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... , Haemolytic disease ... glomerulonephritis, Systemic lupus ... Examples: Contact dermatitis ... #types #allergy
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
When the specific allergen ... during hemolytic disease ... , and systemic lupus ... - Contact dermatitis ... #Diagnosis #Reactions
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... released during an allergic ... reaction or asthma ... Or Inflammatory Reactions ... Colitis and Crohn’s Disease
Peritoneal Dialysis Fluid Appearance and Color - Differential Diagnosis • Cloudy: Peritonitis, Intraperitoneal disease (appendicitis, cholecystitis,
Intraperitoneal disease ... Retroperitoneal disease ... amphotericin B), Allergic ... reaction (increased ... #Diagnosis #nephrology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Other: Transfusion reaction ... usually IgG) (e.g. lupus ... - Transfusion reaction ... Extravascular #Causes #differential ... #diagnosis #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Pigmented Purpuric Dermatosis ... fever • Drug reactions ... Vasculopathy #Purpura #Differential ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... inflammation Others: • Lupus ... such as systemic lupus ... , drug reactions ... #diagnosis #rheumatology
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