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diagnosis rheumatology differential hematology oncology skin activation allergic allergy cryoglobulinemia cryoglobulins cutaneous definitions erythematosus joint macrophage management manifestations mas myelodysplastic
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Gravis, Graves' Disease ... Type III Hypersensitivity ... • Ex: Systemic Lupus ... , Contact Dermatitis ... #Classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... • Autoimmune diseases ... • Hypersensitivity ... (e.g. systemic lupus ... #classification
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Palpable purpura • Hypersensitivity ... vasculitis • ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... Sarcoidosis #dermatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Kasabach-Merritt syndrome ... Pigmented Purpuric Dermatosis ... : • Hypersensitivity ... Associated - SLE ... #nonpalpable #dermatology
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
appearing during the disease ... Neutrophilic dermatosis ... dermatomyositis, SLE ... leukocytoclastic vasculitis ... #oncology #clinical
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Classification: ... • Type-I Interferonopathies ... Clinical Features
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... lesions-interstitial keratitis ... such as systemic lupus ... , and SLE) • Urinalysis ... #rheumatology #classification
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... such as certain types ... Leukocytoclastic vasculitis ... - Lupus - Leukemia ... #diagnosis #dermatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... Clinical Presentation ... SJIA], systemic lupus ... erythematosus [SLE ... • Drug-induced hypersensitivity
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