11 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Vesicopustule on erythematous ... lesions • Discoid lupus ... erythematosus ... #dermatology ... #differential #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... lupus erythematosus ... lupus erythematosus ... Chronic B-cell activation ... #Diagnosis #Rheumatology
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
Bullous systemic lupus ... erythematous ... Vesiculobullous #SkinRash ... #dermatology #Differential ... #Diagnosis #Algorithm
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
appearing during the disease ... Neutrophilic dermatosis ... dermatomyositis, SLE ... #differential #diagnosis ... #dermatology #oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
such as systemic lupus ... erythematosus, ... strong sign of cutaneous ... , and SLE) • Urinalysis ... #rheumatology #
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... : - 10% SLE or ... Henoch-Schönlein purpura) • Cutaneous ... (e.g. systemic lupus ... erythematosus (
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... erythematosus ... SLE], AOSD) • Infection ... #Syndrome #Diagnosis ... #Management #Hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... , such as SLE, atherosclerotic ... ischemia • Skin: Erythematous ... - interstitial keratitis ... #Rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... gangrenosum • Cutaneous ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Most common extra cutaneous ... , breast CA - Hematologic ... ’s syndrome - Lupus ... #dermatology #oncology