11 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Palpable purpura ... lesions • Discoid lupus ... erythematosus ... #dermatology ... #differential #diagnosis
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
: CTD: SLE, RA related ... Vessel: Petechiae, Palpable ... Erythema elevatum ... : • Behcet Disease ... #dermatology #rheumatology
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
appearing during the disease ... Neutrophilic dermatosis ... dermatomyositis, SLE ... #differential #diagnosis ... #dermatology #oncology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... Pigmented Purpuric Dermatosis ... reactions • Erythema ... #hematology #rheumatology ... #dermatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Neutrophilic dermatosis ... gangrenosum • Cutaneous ... leak syndrome • Erythema ... Subcorneal pustular dermatosis ... Paraproteinemias #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: erythematous nodules ... : • Behçet Syndrome ... erythematosus, ... -> causing palpable ... , and SLE) • Urinalysis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
) • Cutaneous Lesions ... multiforme-like lesions, palpable ... Oral aphthae : SLE ... • Arthritis: SLE ... : monoclonal TNF-aIpha
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
febrile neutrophilic dermatosis ... with systemic disease ... Most common extra cutaneous ... ’s syndrome - Lupus ... #dermatology #oncology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Clinical triad of Palpable ... • Autoimmune diseases ... Henoch-Schönlein purpura) • Cutaneous ... (e.g. systemic lupus ... erythematosus (
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... , such as SLE, atherosclerotic ... : Erythematous nodules ... • Behcet syndrome ... #Rheumatology