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differential rheumatology oncology classification hairloss causes clinical cryoglobulinemia cryoglobulins diffuse focal hair joint loss manifestations monoclonal myelodysplastic pain paraproteinemias rashes
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... erythematosus ... #dermatology ... #differential #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... lupus erythematosus ... lupus erythematosus ... Chronic B-cell activation ... #Diagnosis #Rheumatology
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
appearing during the disease ... Neutrophilic dermatosis ... dermatomyositis, SLE ... #differential #diagnosis ... #dermatology #oncology
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Diagnosis Framework ... lupus erythematosus ... : Lupus erythematosus ... , Loose anagen syndrome ... #dermatology #Hairloss
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
• Loose anagen syndrome ... Disease • ... Discoid lupus erythematosus ... #dermatology #Differential ... #Diagnosis #Algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
: erythematous nodules ... such as systemic lupus ... erythematosus, ... , and SLE) • Urinalysis ... #rheumatology #
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... • Autoimmune diseases ... Henoch-Schönlein purpura) • Cutaneous ... (e.g. systemic lupus ... erythematosus (
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Most common extra cutaneous ... , breast CA - Hematologic ... - Lupus - Leukemia ... #diagnosis #dermatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... gangrenosum • Cutaneous ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... , such as SLE, atherosclerotic ... : Erythematous nodules ... - interstitial keratitis ... #Rheumatology
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