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diagnosis differential hematology vasculitis classification oncology erythematosus monoclonal syndrome systemic champs clinical complement cryoglobulins diseases gammopathy hypocomplementemia low management mgus
Renal Involvement in Systemic Lupus Erythematosus Dr. Laurent ARNAUD @Lupusreference #Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Lupusreference #Renal #diseases ... #SLE #Systemic ... #venn #nephrology ... classification #types ... #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... : - 10% SLE or ... Henoch-Schönlein purpura) • Cutaneous ... (e.g. systemic lupus ... classification #rheumatology
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Secondary: CTD: SLE ... Urticarial/LCV) - Cryoglobulinemic ... Vasculitis: • Behcet Disease ... Vasculitis #skin #dermatology ... #rheumatology #
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Mnemonic C - Cryoglobulinemia ... Chain deposition disease ... 1 (50%-80%), type ... S - Systemic Lupus ... #differential #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... scarring • Subacute cutaneous ... Non-autoimmune rheumatologic ... • Type-I Interferonopathies ... Erythematosus #Diagnosis #Rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Pigmented Purpuric Dermatosis ... vasculitis/HSP • Cryoglobulinemia ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
POEMS, AL amyloid, Cryoglobulinemia ... nemaline myopathy Cutaneous-centered ... immunotactoid GN, Type ... Ig deposition disease ... Differential #Diagnosis #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... • Neutrophilic dermatosis ... gangrenosum • Cutaneous ... to cold IgG • Lupus ... Paraproteinemias #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
aphthous ulcers, cutaneous ... such as systemic lupus ... strong sign of cutaneous ... vasculitis, and SLE ... differential #diagnosis #rheumatology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Most common extra cutaneous ... such as certain types ... ’s syndrome - Lupus ... Syndrome #diagnosis #dermatology
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