6 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Demyelinating Syndrome ... Cerebrovascular Disease ... #CNS #neurology ... cerebritis #diagnosis #management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis ... activation of an ... Disorders: - SLE ... Myelitis Treatment ... #management #neurology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... neuropathy • Transverse ... Myelitis • Psychosis ... : Drug induced SLE ... Chronic B-cell activation
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... erythematosus [SLE ... • Drug-induced hypersensitivity ... Treatment: • Corticosteroids ... #Management #Hematology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
sclerosis - Transverse ... myelitis - Neuromyelitis ... Sarcoidosis, Behcet disease ... - SLE, Scleroderma ... MCTD, Sjogren syndrome
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... peripheral neuropathy, transverse ... myelitis • 8%- ... Adenocarcinoma Treatment ... Rheumatology #Diagnosis #Management