13 results
Renal Involvement in Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Lupusreference #Renal #diseases ... #SLE #Systemic ... #Lupus #Erythematosus ... #venn #nephrology ... classification #types
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Decade Skin Disease ... rheumatologic diseases ... (e.g. thyroid disease ... ) • Kikuchi disease
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE)
SLE patient develops
approach to kidney disease ... erythematosus ( ... Perform Kidney Biopsy ... Non-LN Kidney Disease ... #nephrology #biopsy
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... SLE) Clinical ... Cerebrovascular Disease ... #SLE #CNS #neurology ... cerebritis #diagnosis #management
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
during hemolytic disease ... Complement activation ... , and systemic lupus ... erythematosus ... - Contact dermatitis
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
to complement activation ... reaction, Haemolytic disease ... glomerulonephritis, Systemic lupus ... erythematosus Type ... Examples: Contact dermatitis
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Peripheral edema, Disease-specific ... vasculitis, Behcet disease ... Goodpasture's Disease ... dysmorphic RBCs) • Disease-specific ... differential #diagnosis #nephrology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
highly inflammatory disease ... Adult-onset Still disease ... • Kawasaki disease ... of underlying disease ... SLE], AOSD) • Infection
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Studies in Rheumatic Diseases ... erythematosus ( ... exclude inflammatory disease ... connective-tissue disease ... #Rheumatic #Disease
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Systemic rheumatic diseases ... disease, drug reactions ... most important diseases ... (GRANULOMATOUS DISEASE ... HBV Kawasaki Disease