13 results
Renal Involvement in Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Lupusreference #Renal #diseases ... #SLE #Systemic ... #Lupus #Erythematosus ... #venn #nephrology ... classification #types
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Gravis, Graves' Disease ... Type III Hypersensitivity ... • Ex: Systemic Lupus ... Erythematosus, ... Syndrome, Contact Dermatitis
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity ... during hemolytic disease ... , and systemic lupus ... erythematosus ... - Contact dermatitis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Decade Skin Disease ... rheumatologic diseases ... (e.g. thyroid disease ... ) • Kikuchi disease
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... SLE) Clinical ... Cerebrovascular Disease ... #SLE #CNS #neurology ... cerebritis #diagnosis #management
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
to complement activation ... reaction, Haemolytic disease ... glomerulonephritis, Systemic lupus ... erythematosus Type ... Examples: Contact dermatitis
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE)
SLE patient develops
Lupus Nephritis ... approach to kidney disease ... erythematosus ( ... Non-LN Kidney Disease ... #nephrology #biopsy
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
highly inflammatory disease ... Adult-onset Still disease ... • Kawasaki disease ... of underlying disease ... SLE], AOSD) • Infection
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... : - 10% SLE or ... vasculitis • Hypersensitivity ... (e.g. systemic lupus ... erythematosus (
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Studies in Rheumatic Diseases ... erythematosus ( ... exclude inflammatory disease ... connective-tissue disease ... #Rheumatic #Disease