10 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... of Systemic Lupus ... Erythematosus (SLE ... Cerebrovascular Disease ... #SLE #CNS #neurology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
central nervous system ... (CNS) involvement ... lupus erythematosus ... ANCA-associated vasculitides ... BEE #Syndromes #neurology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Differential Diagnosis ... • Type-I Interferonopathies ... and CNS • Headache ... #Systemic #Lupus
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... • Autoimmune diseases ... : - 10% SLE or ... Labs/Diagnosis: ... lupus erythematosus
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... • Neutrophilic dermatosis ... to cold IgG • Lupus ... Sneddon-Wilkinson disease ... #Differential #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... inflammation Others: • Lupus ... lesions-interstitial keratitis ... as systemic lupus ... , and SLE) • Urinalysis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis Framework ... Differential Diagnosis ... as SLE, atherosclerotic ... chorioretinitis, CNS ... - interstitial keratitis
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... IV RTA, TYPE I ... RTA Diagnosis: ... ) • Cutaneous vasculitis ... Vasculitis: •
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
febrile neutrophilic dermatosis ... disease. ... such as certain types ... Leukocytoclastic vasculitis ... ’s syndrome - Lupus
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
disorders, including systemic ... lupus erythematosus ... (SLE), Sjögren’ ... ANCA-associated vasculitis ... and the systemic