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rheumatology differential neurology anca antineutrophil antinuclear cryoglobulinemia cryoglobulins diseases management manifestations myelitis neuromyelitis optica symptoms transverse types vasculitides
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antibody) and ANCA ... ) • Systemic lupus ... erythematosus ... in drug-induced SLE ... #antibodies #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Classification: ... lupus erythematosus ... • Libman-Sacks endocarditis ... #Systemic #Lupus
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... as systemic lupus ... purpura: strong sign ... LFT • ESR • ANA ... , and SLE) • Urinalysis
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
pain • Extra-CNS complications ... autoimmune disorders (Systemic ... lupus erythematosus ... Manifestations #diagnosis ... #signs
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... • Autoimmune diseases ... cytoplasmic antibody ... lupus erythematosus ... #types #classification
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
as SLE, atherosclerotic ... purpura: Strong sign ... ischemia • Skin: Erythematous ... polyangiitis • No ... often causes arthritis
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Bilateral signs ... , SLE or Sjogren's ... Disorders: - SLE ... - Sjogren - Vasculitis ... Antiamphiphysin antibodies
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