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rheumatology ana differential classification antibody arthritis autoantibodies cryoglobulinemia cryoglobulins diseases inflammatory laboratory management neurology patterns rheumatic rheumatoid syndromes table tafro
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... ) • Systemic lupus ... erythematosus ... #ANCA #Antineutrophil ... #antibodies #diagnosis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... lupus erythematosus ... lupus erythematosus ... lupus erythematosus ... : Lupus (SLE), Systemic
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
BEE Syndromes - ... • Systemic lupus ... erythematosus ... vasculitides • ... #Syndromes #neurology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Differential Diagnosis ... deviation • Jaccoud arthropathy ... lupus erythematosus ... #Systemic #Lupus
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... as systemic lupus ... erythematosus, ... ) pattern: antibodies ... , and SLE) • Urinalysis
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... overlap syndromes ... #lupus #erythematosus ... #diagnosis #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... • Autoimmune diseases ... : - 10% SLE or ... DDX: • ANCA (Antineutrophil ... lupus erythematosus
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
affected joint • Systemic ... lupus erythematosus ... (SLE) - Antinuclear ... double-stranded DNA antibodies ... ACE level, CXR, ANCA
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
lupus erythematosus ... (SLE), Sjögren’ ... s syndrome, ANCA-associated ... vasculitis - Infectious ... is thought to be
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