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diagnosis erythematosus neurology antinuclear autoimmune classification management mimickers myelitis myopathy myositis spinal spinalcord transverse vasculitides vasculitis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... (SLE), Systemic ... : Lupus (SLE), Systemic ... #rheumatology #diagnosis ... #differential
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Auto-Antibodies ... Diagnosis and Lupus ... #Systemic #Lupus ... #signs #symptoms
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... • Anti-Ro/SSA autoantibodies ... permanent alopecia Differential ... : • Symptoms limited ... #Systemic #Lupus
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Spinal Cord Disorders ... and signs below ... - SLE, Scleroderma ... , Systemic sclerosis ... #algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Symptoms (Sx) in ... purpura: strong sign ... LFT • ESR • ANA ... ) pattern: antibodies ... SLE) • Urinalysis
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Bilateral signs ... and/or symptoms ... Evaluate for NMO, SLE ... Antiamphiphysin antibodies ... #differential
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Gottron sign) ... • Shawl sign • ... pattern of muscle ... Mechanic's hands Autoantibodies ... • Conduction system
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