17 results
Renal Involvement in Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Erythematosus ... #Erythematosus ... #venn #nephrology ... classification #types ... #rheumatology
Lupus Nephritis Classification Algorithm

#Lupus #Nephritis #Classification #Algorithm #diagnosis #differential #types #rheumatology #nephrology #renal
Lupus Nephritis ... Classification #Algorithm #diagnosis ... #differential #types ... #rheumatology # ... nephrology #renal
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Mnemonic C - Cryoglobulinemia ... S - Systemic Lupus ... Erythematosus ( ... CHAMPS #Mnemonic #diagnosis ... #differential #hematology
Renal involvement in 35% of mixed cryoglobulinemia vasculitis 
Associated with : 
 • Absence of skin
neuropathy • Type ... min/1.73 m2 at diagnosis ... • Dialysis at diagnosis ... Vasculitis #Management #Rheumatology ... #Nephrology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Labs/Diagnosis: ... (e.g. systemic lupus ... erythematosus ( ... Cryoglobulins #diagnosis ... #rheumatology #
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
- Differential Diagnosis ... • Contact dermatitis ... Bullous systemic lupus ... erythematous ... Vesiculobullous #SkinRash
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
conjunctivitis Type ... • Ex: Systemic Lupus ... Erythematosus, ... Syndrome, Contact Dermatitis ... Classification #Diagnosis
Cutaneous Lupus Erythematosus
 • Acute Cutaneous Lupus (ACLE)
 • Neutrophilic Dermatoses 
 • Vascular Lesions
 •
Cutaneous Lupus ... Erythematosus ... #Erythematosus ... #diagnosis #types ... #venn #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... #Erythematosus ... #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity Types ... , and systemic lupus ... erythematosus ... - Contact dermatitis ... Pathophysiology #Allergy #Diagnosis